Hello James,
As in the help section says;
Example
You want products for the same customer on the same route to be packed together. In this IMG activity, you select the values Ship-To Party and Route. All delivery items with the same criterion then receive the same consolidation group, and can be packed together.
This works like a packing group. You can group or split delivery items based on consolidation group. Choose appropriate option for your case in customizing then create delivery. You will see CG number in each delivery item.
First try to customize having different consolidation group for different routes, then we may help on other adjustments.
Best regards
Serhan